The PhD programme ’Molecular Biology and Genetics’ comprises a large number of projects within molecular life sciences. Even though projects are not necessarily limited to the fields described below, the list gives a comprehensive overview of the activities at the Department of Molecular Biology and Genetics:
Research facilities available:
The PhD programme in Molecular Biology and Genetics allows students to take advantage of a range of modern and advanced technologies in addition to standard molecular biology methododologies. Advanced methods include: Next generation sequencing, DNA array technology, greenhouses and controlled environment cabinets for growth of transgenic plants, stables for transgenic animals, mink breeding facilities, facilities for zebrafish, class 2 cell culture facilities, macromolecular x-ray crystallography, biophysics equipment for measurements of kinetic/equilibrium parameters, 3D molecular graphics, nano-drop macromolecular crystallization equipment, high resolution protein purification, fermentation, and large scale protein production.
The PhD programme is based at the Department of Molecular Biology and Genetics and is affiliated with the following Danish National Research Foundation (Danmarks Grundforskningsfond) centres: Centre for mRNP Biogenesis and Metabolism, Carb - Centre for Carbohydrate Recognition and Signalling, Pumpkin - Centre for Membrane Pumps in Cells and Disease as well as the Danish-Chinese Center for Protease and Cancer.
The Department of Molecular Biology and Genetics has a strong profile in basic research and a significant fraction of PhD students therefore continue with an academic career after completing their degree, usually as post docs in laboratories abroad. Many of these former students eventually return to Denmark as new group leaders at universities and other research institutions. A large part of the department also deals with applied research and candidates from these fields often find employment in the pharmaceutical or agricultural industries. Students from the PhD programme also work with teaching (higher education and high school) and in biotech companies in Denmark and abroad.
The PhD programme is associated with the Department of Molecular Biology and Genetics, which is situated at two locations in the Aarhus University campus (“Biokæden”, C. F. Møllers Allé 130 and Forskerparken, Gustav Wieds Vej 10c) and at two external locations at the agricultural Research Centre Foulum near Viborg and AU Flakkebjerg near Slagelse.
A large part of the projects of the PhD programme involve interaction between molecular biology and medicine and are therefore naturally carried out in collaboration with research groups at AU Health. These projects are mainly aimed at 1) understanding and preventing the development of diseases, 2) improving diagnostic methods based on a molecular understanding of human diseases, and/or 3) developing novel therapeutic approaches towards human diseases. Some projects focus on understanding protein function, because such knowledge is required for a molecular understanding of disease. Other projects focus at understanding disease at the level of the genome, or involve animal model systems. The PhD programme is a partner in (?) the European Graduate School in Animal Breeding and Genetics (EGS-ABG, www.egsabg.eu).